What is Glucosamine?
Glucosamine is a compound found naturally in the body, it provides a building block for the cartilage within the body containing sugar and protein, and is a form of amino sugar.
Glucosamine is used by the body to repair damaged tissues like cartilage, heart valves, mucous membranes and synovial fluid - the jelly like substance that fills the joints.
These compounds have also been known to stimulate the production of cartilage as well as repairing it, helping to re-build cartilage and can even produce more.
It is also present in your blood where it is necessary for the production of hyaluronic acid which is essential to heal skin injuries.
history and origin of Glucosamine
found naturally in the body can be man made and obtained from natural
sources as a supplement.
Naturally it is found in sea creatures
such as exoskeletons or crab shells, lobsters, and other shell fish
which live on the sea bed.
Glucosamine was been used in prize thoroughbreds,
cats, dogs, and even exotic animals before it was studied in humans.
There has now been over forty years studying taken place on humans
According to research Glucosamine was being used
on humans in the 1960's by physicians to provide some relief for
people suffering from osteoarthritis.
Glucosamine became very popular
in the United States in the mid 1990's, and is now the most popular
selling dietary supplement with sales of $200 million per year.
It is now also a fast growing favourite supplement in the UK too.
problems can Glucosamine help with?
can help with a variety of conditions, but is best known for its
healing properties for osteoarthritis. Here are some of the conditions
that can be helped by Glucosamine:
A 'wear and tear' condition which
affects the joints mobility and health. It can start in your teens
or as you get older, leaving your joints sore, red and inflamed.
Glucosamine helps repair and keep cartilage healthy, so can help
the pain and swelling of the joints, as well as even producing new
Arthritis (especially jaw arthritis) -
making the jaw stiff, painful and inflamed. Glucosamine helps repair
and build cartilage so can be used to help this condition by relieving
the jaw of pain and stiffness, making the joints more flexible and
supple. " Blood disorders - blood clotting and thickness can be
helped by this supplement. Glucosamine has properties which can
help to thin blood, by relieving the blood of stickiness.Chronic
- A condition which includes swelling of the
legs, varicose veins, pain, itching and skin changes. Although not
researched much, it is possible that Glucosamine could help with
this syndrome.In some cases Rheumatoid arthritis
- An autoimmune
disease that causes inflammation of the joints, the tissues around
the joints and the organs. Glucosamine has healing properties for
arthritis and although not much research has been done on treatment
with Glucosamine for this disease it is possible it could help to
take away the pain and swelling. In some cases inflammatory bowel
- Two chronic diseases that cause inflammation of the intestine,
ulcerative colitis and Crohn's disease. Some preliminary research
has suggested that Glucosamine could help as an additive to medicine
to help reduce the swelling of the intestines. Temporomandibular
joint (TMJ) disorders
- This disorder can have a variety of symptoms
such as; headaches, earaches, dull aching facial pain and tenderness
of the jaw muscles. Not much research has been done to provide sufficient
evidence that Glucosamine can defiantly help ease these symptoms,
but it is suggested that it may help in some people. Some muscle
and tendon injuries
- Glucosamine helps to repair damaged cartilage
including the muscle and tendon tissues so could help strains, swelling
and pain on muscles and tendons although little research has been
conducted to prove its effect. Some skin conditions
has healing properties for skin, so may help with certain skin conditions,
although little research has been done to prove this. Glucosamine
is used in some bandages to help stop bleeding and help heal surgical
incisions and scars.
What recent scientific tests that have been made on Glucosamine?
There has been many tests and research done on Glucosamine which
provides results to show it has worked very well with particular
Many health professionals believe Glucosamine either
by itself or combined with chondroitin sulphate can be effective
to use as treatment for osteoarthritis. Two more recent studies
have lent additional proof that Glucosamine can make a difference
in helping osteoarthritis. The studies found positive results in
hip and especially knee osteoarthritis. These studies had a 'positive'
result where there was 25% more improvement in the treatment group
compared with the placebo group.
The largest ever trial on Glucosamine
is currently being studied in the USA by the National Institutes
of Health within the USA. Thirteen research centres across the USA
are involved, and the University of Utah is co-ordinating the research.
There are 1,500 people taking part and the first results from the
trial have just been finished. There were positive results and they
showed that not only did Glucosamine help the pain and swelling,
but it also in combination with chondroitin stopped the progression
of the disease and helped to re-build damaged and new cartilage.
Other studies on humans have also shown benefits for treating general
osteoarthritis, like pain relief, possible anti-inflammatory effects
and improved joint function. There has also been some research to
suggest that in some people Glucosamine can slow down cartilage
damage in OA. Glucosamine is widely used for this disease and has
helped relief the suffering of many people.
Many other recent studies
published in Lancet (medical journal) have also been carried out
on Glucosamine use in osteoarthritis and they noted a few key points
about Glucosamine effects. The onset of reduced symptoms does not
occur until around several weeks after first taking Glucosamine,
and the benefits continue up to two months after stopping taking
Glucosamine. They also found no evidence to suggest that continued
use reduces the effects of Glucosamine.
Much research has been done
to provide evidence that Glucosamine works effectively at treating
osteoarthritis, but it also can be used as a treatment for other
conditions and problems. Arthritis in the jaw has also had effectiveness
from being treated with Glucosamine as well as rheumatoid arthritis
in some people.
Some studies also show that Glucosamine had the
same affects as the standard treatment that is used to treat mild
to moderate arthritis which is non-steroidal anti-inflammatory drugs.
The same research has also suggested that Glucosamine can also help
to slow down the onset of arthritis.
Glucosamine has also been used
to help keep your skin healthy. It helps not only keeping the skin
healthy but also for repairing skin, which is why Glucosamine plays
a major role in the healing of surgical incisions and wounds. Some
studies have shown that when people have taken Glucosamine before
having surgery, their scars and skin have healed quicker then people
who hadn't. A hemostatic bandage which has Glucosamine within it
has also been introduced and used for the control of vascular bleeding.
In some small studies Chrohn's disease, inflammatory bowel disease
and ulcerative colitis have shown promising effects as well from
treatment with Glucosamine.
Glucosamine safe to take?
All herbal products are governed by the Medicines and Healthcare
products Regulatory Agency (MHRA) and the Foods standards agency
in the UK. There is no guarantee that Glucosamine will be safe to
take for everyone as it is a natural supplement and can affect people
in different ways.
have not had any safety problems with this supplement, and few side
affects have been noted. You should always read the label of products,
and if concerned should consult your doctor before taking this supplement.
If you have a medical condition always consult your doctor before
taking any supplement. If any side effects are felt then always
stop taking the supplement and consult your doctor.
shouldn't take Glucosamine?
There are a few groups
of people who shouldn't take Glucosamine these are:
it safe to take with other supplements and drugs?
- Pregnant and
breastfeeding women, due to lack of safety evidence.
- People with
diabetes or sugar level conditions, because Glucosamine could effect
the glucose regulation and insulin sensitivity.
- There are also
no known effects of long term use of Glucosamine, so long time users
may want to be cautious of any unusual symptoms.
- A patient with
an allergy to shellfish, as Glucosamine is made from shellfish and
may cause a reaction.
- People who have a blood thinning condition,
or are on blood thinning medicines. Glucosamine has a thinning effect
on the blood, so people with thin blood should be careful when taking
this supplement and always consult their doctor.
- Children and
babies should not take Glucosamine as no studies have been completed
to show that it is safe for them to take.
although a natural remedy should be used with care. You should consult
your doctor if you are taking any other medicines, or supplements
before taking Glucosamine. A lot of people are afraid of consulting
their doctor on this matter as they think that their doctor would
not agree to alternative medicines. Most doctors are in favour of
alternative medicines, and will help you anyway they can with medicine
reactions and herbal reactions.
You should also consult your doctor
of any other medicines you take apart from the ones they have prescribed
you, and of any herbal, mineral, or vitamin supplement you intend
to take. Some herbal supplements can react with some drugs so it
is very important that your doctor knows. If you become aware of
any side effects then make sure you consult your doctor as it could
be a reaction between medicines. It is also important to tell your
doctor or physician if you are allergic to any supplement or medicine
before taking them.
feedback on Glucosamine
Many Doctor's have agreed that Glucosamine does work and that it
is a beneficial supplement to take. Doctor's have been looking into
the research that has been established about Glucosamine.
Some doctors and physicians have noted the effects that Glucosamine
can have and have suggested it may even be safer to take for arthritis
then the normal Non-Steroidal Anti-Inflammatory Drugs (NSAIDS).
This is due to the fact that NSAIDS carry a large risk of side effects,
and Glucosamine has shown very little side effects.
also suggest more research to be done on how it helps to stop or
even reverse the effect of cartilage degeneration. Although it is
hard to find people with osteoarthritis who are not taking Glucosamine
now to do the research, this suggests that beneficial effects must
Many doctors are now open to looking at alternative
medicines, so do not be afraid to talk to your doctor about it.
The only downside that some doctors suggest for Glucosamine is that
it can be very expensive to take. Not only this but also that it
is unlikely that it will ever be registered as a medicine so it
could not be prescribed and received on the NHS.
Dosage, how much should I take and who can take it?
doses are based on scientific research, expert opinions, and publications,
you should consult your doctor if you have any queries on dosage
for this product.
Standardization is a process which measures different
chemicals in products to try and make different preparations similar
to one anther. This process is used to help make Glucosamine into
a tablet. Most Glucosamine is in a tablet form to take orally, but
you can also find Glucosamine crystals, which some people prefer.
(18 years and older)
Most studies have used 500mg
strength Glucosamine to take three times daily, but it is also available
in 1000mg strength and 1500mg too. It is not recommended to take
more then 1500mg per day. Some publications have recommended the
dosage of 20mg per kilogram of body weight daily. One study did
also use 2000mg per day for 12 weeks on its participants. Only limited
research has used 1500mg of crystalline powder (Glucosamine crystals)
for oral consumption before. Depending on the stage of your condition
or disease, you could need different doses; it is always advisable
to check with your doctor before deciding what strength you would
like to take.
Children and young adults (younger than 18 years)
There has not been enough research that has been studied on children
to prove that Glucosamine is safe to use on them. Some preliminary
research was done on children who suffered from inflammatory bowel
syndrome with small amounts between 3 and 6 grams daily. Some research
has also shown that MSM (methylsulfonylmethane) has had a connection
with autism in some children. MSM is sometimes marketed with Glucosamine
and this should be avoided by children as studies have shown to
be unclear to what effects it can have.
are the side effects and warnings of taking Glucosamine?
has been known to have some side effects in certain people these
are; upset stomach, drowsiness, insomnia, headache, skin reactions,
nail toughening and sun sensitivity. There has also been rare reports
of other symptoms such as; loss of appetite, vomiting, nausea, abdominal
pain, constipation, diarrhoea, and heartburn. In several people
a temporary increase in heart rate and blood pressure has also occurred.
In human research a dosage of 500mg three times a day has been tolerated
with no side effects for up to 90 days. In a three year trial and
some short term trials the number of adverse events in the patients
taking the Glucosamine was the same as those taking the placebo
It is still unclear whether Glucosamine affects blood sugar
levels, as some research shows no effect and several others have
shown an effect. People with diabetes are advised to be cautious
when taking Glucosamine and are always advised to consult their
In some theories Glucosamine has been suggested to
increase the risk of bleeding. Patients with certain blood disorders
should consult a doctor before taking Glucosamine.
There have also
been some reports which link Glucosamine with asthma exacerbations.
With not much research conducted on this issue asthma patients might
want to avoid, or consult their doctor before taking Glucosamine.
Pregnant and breastfeeding women should avoid Glucosamine as there
is not enough scientific evidence to suggest that it is safe for
this group to take.
Adnominal amounts of proteins have also been
reported in several cases, although the clinical meaning of this
is unclear. The main way for the body to dispel of Glucosamine is
Some preliminary evidence suggests that Glucosamine
could modulate the immune system although clinical research has
not proved this.
This information (and any accompanying material) provided is not intended to replace the attention or advice of a physician or other health care professionals. Anyone wishing to embark on any dietary, drug, exercise, or other lifestyle change intended to prevent or treat a specific disease or condition, or for people who are pregnant should first consult and seek clearance from a qualified health care professionals. The information provided on this site is as accurate as possible. We not accept responsibilities or liability for any inaccuracies.
Buy One Get One Free Glucosamine at Simply Supplements